Maternal effects on anogenital distance in a wild marmot population

Abstract

In mammals, prenatal exposure to sex steroid hormones may have profound effects on later behavior and fitness and have been reported under both laboratory and field conditions. Anogenital distance is a non-invasive measure of prenatal exposure to sex steroid hormones. While we know that intra-uterine position and litter sex ratio influence anogenital distance, there are other, heretofore unstudied, factors that could influence anogenital distance, including maternal effects. We capitalized on a long-term study of wild yellow-bellied marmots (Marmota flaviventris) to study the importance of maternal effects on explaining variation in anogenital distance and found significant effects. The strength of these effects varied annually. Taken together, our data highlights the strong variability due to environmental effects, and illustrates the importance of additive genetic and maternal genetic effects on neonatal anogenital distance. We suspect that, as others apply recently popularised quantitative genetic techniques to study free-living populations, such effects will be identified in other systems. Citation: Fouqueray TD, Blumstein DT, Monclús R, Martin JGA (2014) Maternal Effects on Anogenital Distance in a Wild Marmot Population. PLoS ONE 9(3): e92718. doi:10.1371/journal.pone.0092718 Editor: Marià Alemany, University of Barcelona, Faculty of Biology, Spain Received December 4, 2013; Accepted February 25, 2014; Published March 20, 2014 Copyright: ß 2014 Fouqueray et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: DTB was supported by the National Geographic Society, UCLA (Faculty Senate and the Division of Life Sciences), a Rocky Mountain Biological Laboratory research fellowship, and by the NSF (IDBR-0754247 and DEB-1119660 to DTB, as well as DBI 0242960 and 0731346 to the Rocky Mountain Biological Laboratory). RM was supported by postdoctoral fellowships from the Spanish Ministerio de Innovación y Ciencia and the Fulbright program. JGAM was supported by a FRQNT postdoctoral fellowship and the NSF. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have declared that no competing interests exist. * E-mail: marmots@ucla.edu